Advanced Compounded Skincare for Aging, Pigmentation, and Repair

Dr. Rachel Erickson, Naturopath, L.Ac.

Healthy, youthful skin starts with precision care. At Vitality Integrative Care, we create customized compounded skincare formulas that target aging, pigmentation, and repair from the inside out. Using evidence-based ingredients like estriol, peptides, antioxidants, and brightening actives, these advanced topicals restore radiance, firmness, and even tone—tailored uniquely to your skin’s needs.

The Science of Healthy Skin Aging

As we age, our skin naturally produces less collagen, elastin, and protective antioxidants. Sun exposure, stress, hormones, and inflammation accelerate this process, leading to fine lines, uneven tone, and dullness.

Compounded medical skincare offers a more customized and targeted approach than over-the-counter creams — combining active ingredients in precise concentrations tailored to your skin type and goals.

At Vitality Integrative Care, we partner with trusted compounding pharmacies to create advanced, evidence-based topical formulas that support renewal, even tone, and dermal repair.

How Compounded Topicals Differ from Commercial Products

Customized formulations: Doses and combinations are personalized for your skin and tolerance.
High-grade active ingredients: Pharmaceutical-level potency in clean, well-absorbing bases.
Fewer fillers and fragrances: Better for sensitive or reactive skin.
Supervised use: Adjusted based on your progress and seasonal changes.

Featured Compounded Skincare Formulas

E3 Serum – Elegant Estrogen Support for Mature Skin

Key actives: Estriol (E3), hyaluronic acid, bio-identical base

E3 Serum contains estriol, a gentle form of estrogen that supports skin hydration, elasticity, and dermal thickness.
Applied topically, it helps improve:

Skin firmness and fine lines
Dryness or thinning associated with hormonal changes
Collagen production and resilience

It’s often used by peri- and post-menopausal women as part of a topical hormone support plan under physician supervision.
E3 Serum is prescription-only and customized for each patient’s needs.

KC Repair Cream with Bio-Peptides

Key actives: Superoxide dismutase (SOD), DMAE, CoQ10, kinetin

This rich, restorative base is designed to rebuild, protect, and energize skin cells.

Superoxide dismutase (SOD): Neutralizes oxidative stress and UV damage.
DMAE: Supports tone and firmness by stabilizing cell membranes.
CoQ10: Restores mitochondrial energy for improved skin recovery.
Kinetin: A plant cytokinin that promotes smoother texture and even tone.

Together, these ingredients reduce visible aging signs, enhance repair, and restore a natural glow without irritation.

Brightening & Pigment-Balancing Compounds

Uneven pigmentation and sun damage are among the most common skin concerns. Compounded blends offer precise dosing for visible tone improvement while protecting sensitive skin.

1. Hydroquinone 4% / Tretinoin 0.05% / Fluocinolone 0.01% Cream in KC Skin Soothing Serum

This prescription-strength triple formulation works synergistically to improve discoloration and texture:

Hydroquinone 4%: Lightens hyperpigmented areas by inhibiting melanin synthesis.
Tretinoin 0.05%: Boosts cell turnover and smooths fine lines.
Fluocinolone 0.01%: Reduces irritation during treatment.
KC Skin Soothing Serum base: Hydrating, non-greasy, and calming.

2. Hydroquinone 4% / Kojic Acid 4% / Vitamin C 10% in PermE8/W06 Gel

A non-steroidal alternative for pigmentation concerns, this gel provides:

Hydroquinone 4%: Targets sun spots and melasma.
Kojic Acid 4%: Natural pigment modulator, gentle yet effective.
Vitamin C 10%: Antioxidant support for brightness and collagen health.
PermE8/W06 Gel base: Enhances penetration while keeping skin calm and hydrated.

Used in the evening, it helps fade uneven pigmentation and reveal a more radiant complexion.

How to Use These Formulas

Each prescription compound comes with tailored instructions. In general:

Apply a small amount once daily in the evening unless otherwise directed.
Use broad-spectrum SPF 30+ each morning to protect results.
Avoid waxing or harsh exfoliation while using retinoids or hydroquinone.
Periodically rotate or “cycle” treatments to maintain results safely.

Integrative Skin Aging Support

Topical treatments work best alongside internal and lifestyle support:

Antioxidant nutrients: Vitamins C & E, glutathione, and polyphenols
Hormone balance: Bioidentical HRT or botanical adaptogens if indicated
Inflammation control: Anti-inflammatory diet, hydration, and stress reduction

Healthy, vibrant skin reflects systemic balance — inside and out.

The Takeaway

Modern compounded skincare merges medical precision with natural restoration.
Whether addressing pigment changes, dryness, or fine lines, these formulations support your skin’s renewal process with clinical efficacy and personalized care.

If you’d like to explore custom anti-aging or pigment formulas, schedule a skin consultation with Dr. Rachel to design a regimen that fits your complexion, sensitivities, and lifestyle.

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